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Published in Biometrika, 2019
This paper develop an exact construction of knockoffs for variables distributed as hidden Markov models, and builds upon this a principled and versatile method for controlling the false discovery rate in genome-wide association studies.
Recommended citation: Sesia, Sabatti, and Candès. (2019). "Gene hunting with knockoffs for hidden Markov models." Biometrika. 106(1), pages 1-18. https://doi.org/10.1093/biomet/asy033
Published in Biometrika, 2019
Discussion of ‘Gene hunting with knockoffs for hidden Markov models’.
Recommended citation: Sesia, Sabatti, and Candès. (2019). "Gene hunting with knockoffs for hidden Markov models." Biometrika. 106(1), pages 35-45. https://doi.org/10.1093/biomet/asy075
Published in Journal of the American Statistical Association, 2019
This paper introduces a machine for sampling approximate model-X knockoffs for arbitrary and unspecified data distributions using deep generative models. By building upon the existing model-X framework, we thus obtain a flexible and model-free statistical tool to perform controlled variable selection.
Recommended citation: Romano, Sesia, and Candès. (2019). "Deep Knockoffs." J. Am. Stat. Assoc.. 0(0), pages 1-12. https://doi.org/10.1080/01621459.2019.1660174
Published in Nature Communications, 2020
A knockoff-based method for the genetic mapping of complex traits at multiple resolutions, and a large-scale application to the UK Biobank data.
Recommended citation: Sesia, Bates, Katsevich, Candès, and Sabatti. (2020). "Multi-resolution localization of causal variants across the genome." Nature Commun. 11, 1093. https://doi.org/10.1038/s41467-020-14791-2
Published in Stat, 2020
This paper compares two recent methods that combine conformal inference with quantile regression to produce locally adaptive and marginally valid prediction intervals under sample exchangeability, both theoretically and empirically.
Recommended citation: Sesia and Candès. (2020). "A comparison of some conformal quantile regression methods." Stat. 9:e261. http://dx.doi.org/10.1002/sta4.261
Published in Proc. Natl. Acad. Sci. U.S.A., 2020
Flexible and rigorous causal inference from genetic trio data.
Recommended citation: Bates, Sesia, Sabatti, and Candès (2020). "Causal inference in genetic trio studies." Proc. Natl. Acad. Sci. U.S.A., 117 (39) 24117-24126. https://doi.org/10.1073/pnas.2007743117
Published in Advances in Neural Information Processing Systems 33 (NeurIPS 2020, spotlight presentation), 2020
Model-free classification inference that can efficiently adapt to complex data distributions.
Recommended citation: Romano, Sesia, and Candès (2020). "Classification with valid and adaptive coverage." Advances in Neural Information Processing Systems 33. https://papers.nips.cc/paper/2020/hash/244edd7e85dc81602b7615cd705545f5-Abstract.html
Published in Proc. Natl. Acad. Sci. U.S.A., 2020
A knockoff-based method for the genetic mapping of complex traits at multiple resolutions accounting for population structure, and a large-scale application to the UK Biobank data.
Recommended citation: Sesia, Bates, Candès, Marchini, and Sabatti (2020). "Controlling the false discovery rate in GWAS with population structure." Proc. Natl. Acad. Sci. U.S.A., 1180 (40). https://doi.org/10.1073/pnas.2105841118
Published in pre-print, 2021
This paper studies the construction of p-values for nonparametric outlier detection, taking a multiple-testing perspective.
Recommended citation: Bates, Candès, Lei, Romano, and Sesia (2021). "Testing for Outliers with Conformal p-values." arXiv. https://arxiv.org/abs/2104.08279
Published in Advances in Neural Information Processing Systems 33 (NeurIPS 2021, spotlight presentation), 2021
This paper develops efficient conformity scores for non-parametric regression.
Recommended citation: Sesia and Romano (2021). "Conformal Prediction using Conditional Histograms." Advances in Neural Information Processing Systems 33. https://arxiv.org/abs/2105.08747
Published in Biometrika, 2021
This paper develops a method based on model-X knockoffs to find conditional associations that are robust across diverse environments, controlling the false discovery rate.
Recommended citation: Li, Sesia, Romano, Candès, and Sabatti (2021). "Searching for robust associations with a multi-environment knockoff filter." Biometrika. asab055. https://doi.org/10.1093/biomet/asab055
Published in IEEE Journal of Biomedical and Health Informatics, 2021
An application of knockoffs to signal-processing data from biophysics.
Recommended citation: Chia, Sesia, Ho, Jeffrey, Dionne, Candès, and Howe (2021). "Interpretable Classification of Bacterial Raman Spectra with Knockoff Wavelets." IEEE J. Biomed. Health. Inform. . https://doi.org/10.1109/JBHI.2021.3094873
Published in pre-print, 2021
This paper develops a method to increase the power of conditional testing via knockoffs by leveraging prior information in external data sets collected from different populations or measuring related outcomes.
Recommended citation: Li, Ren, Sabatti, and Sesia (2021). "Transfer learning in genome-wide association studies with knockoffs." arXiv preprint . https://arxiv.org/abs/2108.08813
Published in Journal of Pediatric Intensive Care, 2021
This paper studies the prevalence and severity of hyperoxemia among pediatric intensive care unit patients at the Stanford Children’s Hospital.
Recommended citation: Fayazi, Azadeh R., Sesia, Matteo, Anand, Kanwaljeet J. S. (2021). "Hyperoxemia among Pediatric Intensive Care Unit Patients Receiving Oxygen Therapy." J Pediatr Intensive Care. https://doi.org/10.1055/s-0041-1740586
Published in pre-print, 2022
A flexible conformal inference method is developed to construct confidence intervals for the frequencies of queried objects in a very large data set, based on the information contained in a much smaller sketch of those data.
Recommended citation: Sesia and Favaro (2022). "Conformalized Frequency Estimation from Sketched Data." arXiv. https://arxiv.org/pdf/2204.04270
Published in pre-print, 2022
A flexible conformal inference method is developed to construct confidence intervals for the frequencies of queried objects in a very large data set, based on the information contained in a much smaller sketch of those data.
Recommended citation: Einbinder, Romano, Sesia, and Zhou (2022). "Training Uncertainty-Aware Classifiers with Conformalized Deep Learning." arXiv. https://arxiv.org/abs/2205.05878
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Undergraduate course, Stanford University, 2018
Graduate course, Stanford University, 2018
Undergraduate course, Stanford University, 2020
Course page: http://web.stanford.edu/~msesia/stats195/
Undergraduate course, University of Southern California, 2020
Undergraduate course, University of Southern California, 2021
Misc Tutorials, , 2022